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Molecular Chaperones and the Assembly of the Prion Ure2p in Vitro

The protein Ure2 from Saccharomyces cerevisiae possesses prion properties at the origin of the [URE3] trait. In vivo, a high molecular weight form of inactive Ure2p is associated to [URE3]. The faithful and continued propagation of [URE3]is dependent on the expression levels of molecular chaperones...

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Autors principals: Savistchenko, Jimmy, Krzewska, Joanna, Fay, Nicolas, Melki, Ronald
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259649/
https://ncbi.nlm.nih.gov/pubmed/18400756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800728200
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