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Get Back TFIIF, Don’t Let Me Gdown1

In this issue of Molecular Cell, papers by the Price and Roeder labs reveal how the Gdown1 protein antagonizes the general transcription factor TFIIF during RNAPII initiation and elongation, and how the Mediator complex intervenes in this molecular tug-of-war to activate RNAPII.

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Bibliografiske detaljer
Hovedforfatter: Espinosa, Joaquín M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259525/
https://ncbi.nlm.nih.gov/pubmed/22244325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.016
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