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Get Back TFIIF, Don’t Let Me Gdown1

In this issue of Molecular Cell, papers by the Price and Roeder labs reveal how the Gdown1 protein antagonizes the general transcription factor TFIIF during RNAPII initiation and elongation, and how the Mediator complex intervenes in this molecular tug-of-war to activate RNAPII.

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Detalles Bibliográficos
Autor Principal: Espinosa, Joaquín M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259525/
https://ncbi.nlm.nih.gov/pubmed/22244325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.016
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