Structural perturbation in supercoiled DNA: hypersensitivity to modification by a single-strand-selective chemical reagent conferred by inverted repeat sequences.
Bromoacetaldehyde, a reagent which modifies unpaired adenine residues, selectively modifies supercoiled DNA in the region of inverted repeats which are known targets for single-strand-specific nucleases. The reaction is dependent upon the topological state of the molecule, and the absolute importanc...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1983
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC325951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6304622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.10.3097 |
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