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Discovering transcription factor regulatory targets using gene expression and binding data

Motivation: Identifying the target genes regulated by transcription factors (TFs) is the most basic step in understanding gene regulation. Recent advances in high-throughput sequencing technology, together with chromatin immunoprecipitation (ChIP), enable mapping TF binding sites genome wide, but it...

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Detalhes bibliográficos
Main Authors: Maienschein-Cline, Mark, Zhou, Jie, White, Kevin P., Sciammas, Roger, Dinner, Aaron R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259433/
https://ncbi.nlm.nih.gov/pubmed/22084256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr628
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