Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination

Brain-derived neurotrophic factor (BDNF) is involved in neuronal and glial development and survival. While neurons and astrocytes are its main cellular source in the central nervous system (CNS), bioactive BDNF is also expressed in immune cells and in lesions of multiple sclerosis and its animal mod...

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Autori principali: Lee, De-Hyung, Geyer, Eva, Flach, Anne-Christine, Jung, Klaus, Gold, Ralf, Flügel, Alexander, Linker, Ralf A., Lühder, Fred
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2011
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259380/
https://ncbi.nlm.nih.gov/pubmed/22009304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0890-3
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