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Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination
Brain-derived neurotrophic factor (BDNF) is involved in neuronal and glial development and survival. While neurons and astrocytes are its main cellular source in the central nervous system (CNS), bioactive BDNF is also expressed in immune cells and in lesions of multiple sclerosis and its animal mod...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259380/ https://ncbi.nlm.nih.gov/pubmed/22009304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0890-3 |
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