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Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir

Wnt proteins that signal via the canonical Wnt/β-catenin pathway directly regulate osteoblast differentiation. In contrast, most studies of Wnt-related effects on osteoclasts involve indirect changes. While investigating bone mineral density loss in the setting of human immunodeficiency virus (HIV)...

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Detalhes bibliográficos
Main Authors: Santiago, Francisco, Oguma, Junya, Brown, Anthony M.C., Laurence, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259256/
https://ncbi.nlm.nih.gov/pubmed/22142846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.089
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