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Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities

Nicotine conjugate vaccine efficacy is limited by the concentration of nicotine-specific antibodies that can be reliably generated in serum. Previous studies suggest that the concurrent use of 2 structurally distinct nicotine immunogens in rats can generate additive antibody responses by stimulating...

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Detalhes bibliográficos
Main Authors: Pravetoni, M, Keyler, DE, Pidaparthi, RR, Carroll, FI, Runyon, SP, Murtaugh, MP, Earley, CA, Pentel, PR
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259188/
https://ncbi.nlm.nih.gov/pubmed/22100986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.11.004
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