Normalizing for individual cell population context in the analysis of high-content cellular screens

BACKGROUND: High-content, high-throughput RNA interference (RNAi) offers unprecedented possibilities to elucidate gene function and involvement in biological processes. Microscopy based screening allows phenotypic observations at the level of individual cells. It was recently shown that a cell'...

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Detalhes bibliográficos
Main Authors: Knapp, Bettina, Rebhan, Ilka, Kumar, Anil, Matula, Petr, Kiani, Narsis A, Binder, Marco, Erfle, Holger, Rohr, Karl, Eils, Roland, Bartenschlager, Ralf, Kaderali, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259109/
https://ncbi.nlm.nih.gov/pubmed/22185194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-485
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