Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

BACKGROUND: Members of the mammalian nucleotide binding domain, leucine-rich repeat (LRR)-containing receptor (NLR) family of proteins are key modulators of innate immunity regulating inflammation. Our previous work has shown that among the members of this family, NLRP1/NALP1, present in neurons, pl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mawhinney, Lana J, de Rivero Vaccari, Juan Pablo, Dale, Gordon A, Keane, Robert W, Bramlett, Helen M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259063/
https://ncbi.nlm.nih.gov/pubmed/22133203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-123
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