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Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury

Traumatic brain injury (TBI) activates the NALP1/NLRP1 inflammasome, which is an important component of the early innate inflammatory response to injury. We investigated the influence of therapeutic hypothermia on inflammasome activation after TBI. Adult male Sprague–Dawley rats were subjected to mo...

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Detalhes bibliográficos
Main Authors: Tomura, Satoshi, de Rivero Vaccari, Juan Pablo, Keane, Robert W, Bramlett, Helen M, Dietrich, W Dalton
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463887/
https://ncbi.nlm.nih.gov/pubmed/22781337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.99
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