Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

Genome-wide association studies have identified common variation in the CHRNA5–CHRNA3–CHRNB4 and CHRNA6–CHRNB3 gene clusters that contribute to nicotine dependence. However, the role of rare variation in risk for nicotine dependence in these nicotinic receptor genes has not been studied. We undertoo...

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Autors principals: Haller, Gabe, Druley, Todd, Vallania, Francesco L., Mitra, Robi D., Li, Ping, Akk, Gustav, Steinbach, Joe Henry, Breslau, Naomi, Johnson, Eric, Hatsukami, Dorothy, Stitzel, Jerry, Bierut, Laura J., Goate, Alison M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259016/
https://ncbi.nlm.nih.gov/pubmed/22042774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr498
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