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Functional Characterization Improves Associations between Rare Non-Synonymous Variants in CHRNB4 and Smoking Behavior

Smoking is the leading cause of preventable death worldwide. Accordingly, effort has been devoted to determining the genetic variants that contribute to smoking risk. Genome-wide association studies have identified several variants in nicotinic acetylcholine receptor genes that contribute to nicotin...

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Detalhes bibliográficos
Main Authors: Haller, Gabe, Li, Ping, Esch, Caroline, Hsu, Simon, Goate, Alison M., Steinbach, Joe Henry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013067/
https://ncbi.nlm.nih.gov/pubmed/24804708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096753
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