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Sequence-specific responses of restriction endonucleases to bromodeoxyuridine substitution in mammalian DNA.

Substitution of BrdU for dT in mammalian DNA alters the rates of DNA cleavage by restriction endonucleases in a manner that can be related to the specificity of cleavage. A formula is proposed that describes inhibitory and stimulatory contributions arising from the substitution of a Br atom for the...

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Autors principals: Petruska, J, Horn, D
Format: Artigo
Idioma:Inglês
Publicat: 1983
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC325898/
https://ncbi.nlm.nih.gov/pubmed/6304654
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