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Double Deficiency of Tetraspanins CD9 and CD81 Alters Cell Motility and Protease Production of Macrophages and Causes Chronic Obstructive Pulmonary Disease-like Phenotype in Mice

CD9 and CD81 are closely related tetraspanins that regulate cell motility and signaling by facilitating the organization of multimolecular membrane complexes, including integrins. We show that CD9 and CD81 are down-regulated in smoking-related inflammatory response of a macrophage line, RAW264.7. Wh...

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Bibliografische gegevens
Hoofdauteurs: Takeda, Yoshito, He, Ping, Tachibana, Isao, Zhou, Bo, Miyado, Kenji, Kaneko, Hideshi, Suzuki, Mayumi, Minami, Seigo, Iwasaki, Takeo, Goya, Sho, Kijima, Takashi, Kumagai, Toru, Yoshida, Mitsuhiro, Osaki, Tadashi, Komori, Toshihisa, Mekada, Eisuke, Kawase, Ichiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258854/
https://ncbi.nlm.nih.gov/pubmed/18662991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801902200
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