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Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

Lipid-modified Wnt/Wingless (Wg) proteins can signal to their target cells in a short- or long-range manner. How these hydrophobic proteins travel through the extracellular environment remains an outstanding question. Here, we report on a Wg binding protein, Secreted Wg-interacting molecule (Swim),...

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Detalhes bibliográficos
Main Authors: Mulligan, Kimberly A., Fuerer, Christophe, Ching, Wendy, Fish, Matt, Willert, Karl, Nusse, Roeland
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258625/
https://ncbi.nlm.nih.gov/pubmed/22203956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119197109
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