Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis

Copy number variants (CNVs) represent a substantial source of genomic variation in vertebrates and have been associated with numerous human diseases. Despite this, the extent of CNVs in the zebrafish, an important model for human disease, remains unknown. Using 80 zebrafish genomes, representing thr...

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Detalhes bibliográficos
Main Authors: Brown, Kim H., Dobrinski, Kimberly P., Lee, Arthur S., Gokcumen, Omer, Mills, Ryan E., Shi, Xinghua, Chong, Wilson W. S., Chen, Jin Yun Helen, Yoo, Paulo, David, Sthuthi, Peterson, Samuel M., Raj, Towfique, Choy, Kwong Wai, Stranger, Barbara E., Williamson, Robin E., Zon, Leonard I., Freeman, Jennifer L., Lee, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258620/
https://ncbi.nlm.nih.gov/pubmed/22203992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112163109
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