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Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle

In Escherichia coli crosstalk between DNA supercoiling, nucleoid-associated proteins and major RNA polymerase σ initiation factors regulates growth phase-dependent gene transcription. We show that the highly conserved spatial ordering of relevant genes along the chromosomal replichores largely corre...

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Bibliografiske detaljer
Main Authors: Sobetzko, Patrick, Travers, Andrew, Muskhelishvili, Georgi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258614/
https://ncbi.nlm.nih.gov/pubmed/22184251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108229109
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