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Nonplanar peptide bonds in proteins are common and conserved but not biased toward active sites

The planarity of peptide bonds is an assumption that underlies decades of theoretical modeling of proteins. Peptide bonds strongly deviating from planarity are considered very rare features of protein structure that occur for functional reasons. Here, empirical analyses of atomic-resolution protein...

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Main Authors: Berkholz, Donald S., Driggers, Camden M., Shapovalov, Maxim V., Dunbrack, Roland L., Karplus, P. Andrew
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258596/
https://ncbi.nlm.nih.gov/pubmed/22198840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107115108
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