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Development of a rotamer library for use in β-peptide foldamer computational design

Foldamers present a particularly difficult challenge for accurate computational design compared to the case for conventional peptide and protein design due to the lack of a large body of structural data to allow parameterization of rotamer libraries and energies. We therefore explored the use of mol...

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Bibliografski detalji
Glavni autori: Shandler, Scott J., Shapovalov, Maxim V., Dunbrack, Roland L., DeGrado, William F.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079439/
https://ncbi.nlm.nih.gov/pubmed/20446685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja906700x
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