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Dominant Role of HPV16 E7 in Anal Carcinogenesis

Ninety percent of anal cancer is associated with human papilloma viruses (HPVs). Using our previously established HPV transgenic mouse model for anal cancer, we tested the role of the individual oncogenes E6 and E7. K14E6 and K14E7 transgenic mice were treated with dimethylbenz[a]anthracene (DMBA) t...

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Detalhes bibliográficos
Main Authors: Thomas, Marie K., Pitot, Henry C., Liem, Amy, Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258583/
https://ncbi.nlm.nih.gov/pubmed/21999991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.09.018
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