Rapid Detection of rpoB Mutations in Rifampin Resistant M. tuberculosis from Sputum Samples by Denaturing Gradient Gel Electrophoresis

Objective: To establish a rapid detection method for identifying rpoB mutations associated with rifampin (RIF) resistance in sputum specimens. Methods: We detected rpoB mutations directly in 90 sputum specimens collected from suspected tuberculosis patients using PCR-based denaturing gradient gel el...

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Main Authors: Li, Jun, Xin, Jiaojiao, Zhang, Liyuan, Jiang, Longyan, Cao, Hongcui, Li, Lanjuan
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2012
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258557/
https://ncbi.nlm.nih.gov/pubmed/22253562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.3605
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