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Role of MetMAb (OA-5D5) in c-MET active lung malignancies

INTRODUCTION: MetMAb (OA-5D5) is a one-armed monoclonal antibody developed to bind to and inhibit c-MET receptor tyrosine kinase. Though early in clinical testing, this agent holds great promise in diseases thought to be driven by c-MET activation, as evidenced by the phase II results in non-small c...

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Detalhes bibliográficos
Main Authors: Surati, Mosmi, Patel, Premal, Peterson, Amy, Salgia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258451/
https://ncbi.nlm.nih.gov/pubmed/22047509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2011.626762
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