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Structural basis for activation of calcineurin by calmodulin
The highly conserved phosphatase calcineurin plays vital roles in numerous processes including T-cell activation, development and function of the central nervous system, and cardiac growth. It is activated by the calcium sensor calmodulin. Calmodulin binds to a regulatory domain within calcineurin,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258384/ https://ncbi.nlm.nih.gov/pubmed/22100452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.11.008 |
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