Identification of proprotein convertase substrates using genome-wide expression correlation analysis

BACKGROUND: Subtilisin/kexin-like proprotein convertase (PCSK) enzymes have important regulatory function in a wide variety of biological processes. PCSKs proteolytically process at a target sequence that contains basic amino acids arginine and lysine, which results in functional maturation of the t...

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Bibliographic Details
Main Authors: Turpeinen, Hannu, Kukkurainen, Sampo, Pulkkinen, Kati, Kauppila, Timo, Ojala, Kalle, Hytönen, Vesa P, Pesu, Marko
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258279/
https://ncbi.nlm.nih.gov/pubmed/22185580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-618
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