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Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection

BACKGROUND: Galactosyl transferase gene knock-out (GalTKO) swine offer a unique tool to evaluate the role of the Gal antigen in xenogenic lung hyperacute rejection. METHODS: We perfused GalTKO miniature swine lungs with human blood. Results were compared with those from previous studies using wild-t...

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Detalhes bibliográficos
Main Authors: Nguyen, Bao-Ngoc H., Azimzadeh, Agnes M., Schroeder, Carsten, Buddensick, Thomas, Zhang, Tianshu, Laaris, Amal, Cochrane, Megan, Schuurman, Henk-Jan, Sachs, David H., Allan, James S., Pierson, Richard N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258267/
https://ncbi.nlm.nih.gov/pubmed/21496117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3089.2011.00633.x
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