A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters

Generation of gain-of-function transgenic mice by targeting the Rosa26 locus has been established as an alternative to classical transgenic mice produced by pronuclear microinjection. However, targeting transgenes to the endogenous Rosa26 promoter results in moderate ubiquitous expression and is not...

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Detalhes bibliográficos
Main Authors: Tchorz, Jan S., Suply, Thomas, Ksiazek, Iwona, Giachino, Claudio, Cloëtta, Dimitri, Danzer, Claus-Peter, Doll, Thierry, Isken, Andrea, Lemaistre, Marianne, Taylor, Verdon, Bettler, Bernhard, Kinzel, Bernd, Mueller, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258265/
https://ncbi.nlm.nih.gov/pubmed/22253858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030011
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