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AU-Rich Element-Mediated mRNA Decay Can Occur Independently of the miRNA Machinery in Mouse Embryonic Fibroblasts and Drosophila S2-Cells

AU-rich elements (AREs) are regulatory sequences located in the 3′ untranslated region of many short-lived mRNAs. AREs are recognized by ARE-binding proteins and cause rapid mRNA degradation. Recent reports claimed that the function of AREs may be – at least in part – relayed through the miRNA pathw...

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Detaylı Bibliyografya
Asıl Yazarlar: Helfer, Stephanie, Schott, Johanna, Stoecklin, Georg, Förstemann, Klaus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258239/
https://ncbi.nlm.nih.gov/pubmed/22253700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028907
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