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Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm
In mammalian cells, AU-rich elements (AREs) are well known regulatory sequences located in the 3′ untranslated region (UTR) of many short-lived mRNAs. AREs cause mRNAs to be degraded rapidly and thereby suppress gene expression at the posttranscriptional level. Based on the number of AUUUA pentamers...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252268/ https://ncbi.nlm.nih.gov/pubmed/22242014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002433 |
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