The Immunosuppressant FTY720 (Fingolimod) enhances Glycosaminoglycan depletion in articular cartilage

BACKGROUND: FTY720 (Fingolimod) is a novel immunosuppressive drug investigated in clinical trials for organ transplantation and multiple sclerosis. It acts as a functional sphingosine-1-phosphate (S1P) receptor antagonist, thereby inhibiting the egress of lymphocytes from secondary lymphoid organs....

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Main Authors: Stradner, Martin H, Angerer, Hannes, Ortner, Thomas, Fuerst, Florentine C, Setznagl, Daniela, Kremser, Marie-Luise, Hermann, Josef, Graninger, Winfried B
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258222/
https://ncbi.nlm.nih.gov/pubmed/22151889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-279
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