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SV40 deletion mutants lacking the 21-bp repeated sequences are viable, but have noncomplementable deficiencies.

We have constructed deletion mutants of simian virus 40 (SV40) lacking the two tandemly repeated copies or all three copies of the 21-bp repeated sequence located in the origin region. The mutants were viable, but had lower infectivities compared to the wild type. The mutant lacking two copies of th...

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Main Authors: Hartzell, S W, Yamaguchi, J, Subramanian, K N
格式: Artigo
語言:Inglês
出版: 1983
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC325819/
https://ncbi.nlm.nih.gov/pubmed/6298750
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