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Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease
Mitochondrial dysfunction plays a primary role in the pathogenesis of Parkinson's disease (PD), particularly in autosomal recessive forms of the disease caused by mutations encoding PINK1. Although mitochondrial pathology can be demonstrated in many cell types, it is neurons that bear the brunt...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Company of Biologists
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258104/ https://ncbi.nlm.nih.gov/pubmed/22223879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.088260 |
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