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Inconsistencies in Estimating the Age of HIV-1 Subtypes Due to Heterotachy

Rate heterogeneity among lineages is a common feature of molecular evolution, and it has long impeded our ability to accurately estimate the age of evolutionary divergence events. The development of relaxed molecular clocks, which model variable substitution rates among lineages, was intended to rec...

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Detalhes bibliográficos
Main Authors: Wertheim, Joel O., Fourment, Mathieu, Kosakovsky Pond, Sergei L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258043/
https://ncbi.nlm.nih.gov/pubmed/22045998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr266
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