Immunization with Apoptotic Phagocytes Containing Histoplasma capsulatum Activates Functional CD8(+) T Cells To Protect against Histoplasmosis

We have previously revealed the protective role of CD8(+) T cells in host defense against Histoplasma capsulatum in animals with CD4(+) T cell deficiency and demonstrated that sensitized CD8(+) T cells are restimulated in vitro by dendritic cells that have ingested apoptotic macrophage-associated Hi...

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Detalhes bibliográficos
Principais autores: Hsieh, Shih-Hung, Lin, Jr-Shiuan, Huang, Juin-Hua, Wu, Shang-Yang, Chu, Ching-Liang, Kung, John T., Wu-Hsieh, Betty A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257918/
https://ncbi.nlm.nih.gov/pubmed/21911464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05350-11
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