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Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis

Recent studies suggest that cancer stem cells (CSCs) are responsible for cancer resistance to therapies. We therefore investigated how glioblastoma-derived CSCs respond to the treatment of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Neurospheres were generated from glioblastomas...

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Detalhes bibliográficos
Main Authors: Qi, Ling, Bellail, Anita C., Rossi, Michael R., Zhang, Zhaobin, Pang, Hui, Hunter, Stephen, Cohen, Cynthia, Moreno, Carlos S., Olson, Jeffrey J., Li, Shibo, Hao, Chunhai
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257579/
https://ncbi.nlm.nih.gov/pubmed/21877214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0645-6
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