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Revealing a steroid receptor ligand as a unique PPARγ agonist
Peroxisome proliferator-activated receptor gamma (PPARγ) regulates metabolic homeostasis and is a molecular target for anti-diabetic drugs. We report here the identification of a steroid receptor ligand, RU-486, as an unexpected PPARγ agonist, thereby uncovering a novel signaling route for this ster...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257359/ https://ncbi.nlm.nih.gov/pubmed/21986665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.162 |
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