A Functional Variant in ERAP1 Predisposes to Multiple Sclerosis

The ERAP1 gene encodes an aminopeptidase involved in antigen processing. A functional polymorphism in the gene (rs30187, Arg528Lys) associates with susceptibility to ankylosying spondylitis (AS), whereas a SNP in the interacting ERAP2 gene increases susceptibility to another inflammatory autoimmune...

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Bibliografiset tiedot
Päätekijät: Guerini, Franca Rosa, Cagliani, Rachele, Forni, Diego, Agliardi, Cristina, Caputo, Domenico, Cassinotti, Andrea, Galimberti, Daniela, Fenoglio, Chiara, Biasin, Mara, Asselta, Rosanna, Scarpini, Elio, Comi, Giacomo P., Bresolin, Nereo, Clerici, Mario, Sironi, Manuela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257233/
https://ncbi.nlm.nih.gov/pubmed/22253828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029931
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