Discovery of T Cell Antigens by High-Throughput Screening of Synthetic Minigene Libraries

The identification of novel T cell antigens is central to basic and translational research in autoimmunity, tumor immunology, transplant immunology, and vaccine design for infectious disease. However, current methods for T cell antigen discovery are low throughput, and fail to explore a wide range o...

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Main Authors: Hondowicz, Brian D., Schwedhelm, Katharine V., Kas, Arnold, Tasch, Michael A., Rawlings, Crystal, Ramchurren, Nirasha, McIntosh, Martin, D'Amico, Leonard A., Sanda, Srinath, Standifer, Nathan E., Shendure, Jay, Stone, Brad
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257230/
https://ncbi.nlm.nih.gov/pubmed/22253836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029949
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