Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis

Podocytes have a significant role in establishing selective permeability of the glomerular filtration barrier. Sustained renin–angiotensin–aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to ph...

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Bibliografski detalji
Glavni autori: Hsu, Hsiang-Hao, Hoffmann, Sigrid, Di Marco, Giovana S, Endlich, Nicole, Peter-Katalinić, Jasna, Weide, Thomas, Pavenstädt, Hermann
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257043/
https://ncbi.nlm.nih.gov/pubmed/21814176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.250
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