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Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis

Podocytes have a significant role in establishing selective permeability of the glomerular filtration barrier. Sustained renin–angiotensin–aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to ph...

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Detalhes bibliográficos
Main Authors: Hsu, Hsiang-Hao, Hoffmann, Sigrid, Di Marco, Giovana S, Endlich, Nicole, Peter-Katalinić, Jasna, Weide, Thomas, Pavenstädt, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257043/
https://ncbi.nlm.nih.gov/pubmed/21814176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.250
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