Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis

Podocytes have a significant role in establishing selective permeability of the glomerular filtration barrier. Sustained renin–angiotensin–aldosterone system activation is crucial to the pathogenesis of podocyte injury, but the mechanisms by which angiotensin II modulates podocyte survival due to ph...

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Bibliografiske detaljer
Main Authors: Hsu, Hsiang-Hao, Hoffmann, Sigrid, Di Marco, Giovana S, Endlich, Nicole, Peter-Katalinić, Jasna, Weide, Thomas, Pavenstädt, Hermann
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257043/
https://ncbi.nlm.nih.gov/pubmed/21814176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.250
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