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miR-155 regulates HGAL expression and increases lymphoma cell motility

HGAL, a prognostic biomarker in patients with diffuse large B-cell lymphoma and classic Hodgkin lymphoma, inhibits lymphocyte and lymphoma cell motility by activating the RhoA signaling cascade and interacting with actin and myosin proteins. Although HGAL expression is limited to germinal center (GC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dagan, Liat Nadav, Jiang, Xiaoyu, Bhatt, Shruti, Cubedo, Elena, Rajewsky, Klaus, Lossos, Izidore S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257016/
https://ncbi.nlm.nih.gov/pubmed/22096245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-370536
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