Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic–pituitary–adrenal axis

Skeletal muscle catabolism is a co-morbidity of many chronic diseases and is the result of systemic inflammation. Although direct inflammatory cytokine action on muscle promotes atrophy, nonmuscle sites of action for inflammatory mediators are less well described. We demonstrate that central nervous...

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Hlavní autoři: Braun, Theodore P., Zhu, Xinxia, Szumowski, Marek, Scott, Gregory D., Grossberg, Aaron J., Levasseur, Peter R., Graham, Kathryn, Khan, Sheehan, Damaraju, Sambasivarao, Colmers, William F., Baracos, Vickie E., Marks, Daniel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256966/
https://ncbi.nlm.nih.gov/pubmed/22084407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111020
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