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Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic–pituitary–adrenal axis

Skeletal muscle catabolism is a co-morbidity of many chronic diseases and is the result of systemic inflammation. Although direct inflammatory cytokine action on muscle promotes atrophy, nonmuscle sites of action for inflammatory mediators are less well described. We demonstrate that central nervous...

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Detalhes bibliográficos
Main Authors: Braun, Theodore P., Zhu, Xinxia, Szumowski, Marek, Scott, Gregory D., Grossberg, Aaron J., Levasseur, Peter R., Graham, Kathryn, Khan, Sheehan, Damaraju, Sambasivarao, Colmers, William F., Baracos, Vickie E., Marks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256966/
https://ncbi.nlm.nih.gov/pubmed/22084407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111020
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