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Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic–pituitary–adrenal axis
Skeletal muscle catabolism is a co-morbidity of many chronic diseases and is the result of systemic inflammation. Although direct inflammatory cytokine action on muscle promotes atrophy, nonmuscle sites of action for inflammatory mediators are less well described. We demonstrate that central nervous...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256966/ https://ncbi.nlm.nih.gov/pubmed/22084407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111020 |
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