Specific Armadillo Repeat Sequences Facilitate β-Catenin Nuclear Transport in Live Cells via Direct Binding to Nucleoporins Nup62, Nup153, and RanBP2/Nup358

β-Catenin transduces the Wnt signal from the membrane to nucleus, and certain gene mutations trigger its nuclear accumulation leading to cell transformation and cancer. β-Catenin shuttles between the nucleus and cytoplasm independent of classical Ran/transport receptor pathways, and this movement wa...

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Detaylı Bibliyografya
Asıl Yazarlar: Sharma, Manisha, Jamieson, Cara, Johnson, Michael, Molloy, Mark P., Henderson, Beric R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256910/
https://ncbi.nlm.nih.gov/pubmed/22110128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299099
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