A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

The T cell receptor (TCR) orchestrates immune responses by binding to foreign peptides presented at the cell surface in the context of major histocompatibility complex (MHC) molecules. Effective immunity requires that all possible foreign peptide-MHC molecules are recognized or risks leaving holes i...

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Autors principals: Wooldridge, Linda, Ekeruche-Makinde, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John J., Tan, Mai Ping, Dolton, Garry, Clement, Mathew, Llewellyn-Lacey, Sian, Price, David A., Peakman, Mark, Sewell, Andrew K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256900/
https://ncbi.nlm.nih.gov/pubmed/22102287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289488
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