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Inactivated RNA Polymerase II Open Complexes Can Be Reactivated with TFIIE

Transcript initiation by RNA polymerase II (pol II) requires a helicase within TFIIH to generate the unpaired template strand. However, pol II preinitiation complexes (PICs) lose the ability to synthesize RNA very rapidly upon exposure to ATP alone in the absence of other NTPs. This inactivation is...

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Bibliografiset tiedot
Päätekijät: Čabart, Pavel, Luse, Donal S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256861/
https://ncbi.nlm.nih.gov/pubmed/22119917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297572
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