Signal-dependent Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate without Activation of Phospholipase C: IMPLICATIONS ON GATING OF DROSOPHILA TRPL (TRANSIENT RECEPTOR POTENTIAL-LIKE) CHANNEL

In Drosophila, a phospholipase C (PLC)-mediated signaling cascade, couples photo-excitation of rhodopsin to the opening of the transient receptor potential (TRP) and TRP-like (TRPL) channels. A lipid product of PLC, diacylglycerol (DAG), and its metabolites, polyunsaturated fatty acids (PUFAs) may f...

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Bibliographic Details
Main Authors: Lev, Shaya, Katz, Ben, Tzarfaty, Vered, Minke, Baruch
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256851/
https://ncbi.nlm.nih.gov/pubmed/22065576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266585
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