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Signal-dependent Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate without Activation of Phospholipase C: IMPLICATIONS ON GATING OF DROSOPHILA TRPL (TRANSIENT RECEPTOR POTENTIAL-LIKE) CHANNEL
In Drosophila, a phospholipase C (PLC)-mediated signaling cascade, couples photo-excitation of rhodopsin to the opening of the transient receptor potential (TRP) and TRP-like (TRPL) channels. A lipid product of PLC, diacylglycerol (DAG), and its metabolites, polyunsaturated fatty acids (PUFAs) may f...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256851/ https://ncbi.nlm.nih.gov/pubmed/22065576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266585 |
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