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Mitochondrial DNA Mutations in Respiratory Complex-I in Never-Smoker Lung Cancer Patients Contribute to Lung Cancer Progression and associated with EGFR gene mutation

Mitochondrial DNA (mtDNA) mutations were reported in different cancers. However, the nature and role of mtDNA mutation in never-smoker lung cancer patients including patients with EGFR and KRAS gene mutation are unknown. In the present study, we sequenced entire mitochondrial genome (16.5 kb) in mat...

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Bibliographische Detailangaben
Hauptverfasser: Dasgupta, Santanu, Soudry, Ethan, Mukhopadhyay, Nitai, Shao, Chunbo, Yee, John, Lam, Stephan, Lam, Wan, Zhang, Wei, Gazdar, Adi F, Fisher, Paul B, Sidransky, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256258/
https://ncbi.nlm.nih.gov/pubmed/21830212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22980
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